A StageBio team member is a contributing author on a book published to help researchers determine whether pathologic changes observed in laboratory non-human primates (NHP) are spontaneous or the result of other factors. 

Dr. Sarah Cramer, DVM, PhD, DACVP, Director of Medical Device and Neuropathology at StageBio, lends her knowledge to the book titled “Spontaneous Pathology of the Laboratory Non-human Primate.” In chapter three, Dr Cramer and her co-authors describe in detail the characteristics of pathologic changes caused by infectious diseases found in NHPs.

Dr. Cramer is also a contributing writer of chapter 10 in the book, which seeks to provide an overview of the NHP nervous system and explain the characteristics of various nervous system diseases. Topics in this chapter cover the degenerative, inflammatory, neoplastic and other spontaneous changes in the NHP nervous system that occur as a result of disease.

“Far too often, when conducting safety assessment studies, pathologists don’t have access to the reference materials necessary to rule out a spontaneous non-clinical disease pathology as the cause of death in non-human primates. This book was written to be the resource that provides the guidance and clarifications needed to make those kinds of determinations. I’m grateful for the opportunity to share my knowledge and expertise in this area, and I hope pathologists working with primates in safety assessment studies find the book an indispensable companion in the lab.”

— Dr. Sarah Cramer, StageBio Director of Medical Device and Neuropathology

Learn more about the book “Spontaneous Pathology of the Laboratory Non-human Primate” here.