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Coronavirus Pandemic: A Critical Role for Animal Models

The orthopedic device sector of the medical device industry is fast-growing and constantly evolving. Histopathological evaluation of orthopedic devices provides a critical assessment for determining the safety and efficacy of these next-generation biomaterials, especially with continued advancements in technology and designs of orthopedic devices. Proper evaluation of the biocompatibility of orthopedic implants should include advanced histological imaging and processing techniques to better assess tissue response surrounding the implant and to gauge the potential for adverse effects. This is the seventh and final article in this series where we highlight a portion of the article published by Nicolette Jackson et al. discussing the different types of mechanical testing used during the evaluation of orthopedic devices in preclinical animal studies.

This is the fourth article in our ongoing blog series reviewing the 2019 article: "Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-art in Animal Models, Imaging, and Histomorphometry Techniques" by Nicolette Jackson, Michel Assad, Derick Vollmer, James Stanley and Madeleine Chagnon. Today, we'll review pertinent insights into histology techniques used to obtain high quality histology slides for preclinical medical device pathology studies.

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Today we continue our ongoing blog series, a review of the 2019 article Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-art in Animal Models, Imaging, and Histomorphometry Technique by Nicolette Jackson, Michel Assad, Derick Vollmer, James Stanley, and Madeleine Chagnon. As this is a rather comprehensive article, we are offering a brief summary here with the recommendation that you read the original article to understand more about medical device histopathology.