This is the fourth article in our ongoing blog series reviewing the 2019 article: "Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-art in Animal Models, Imaging, and Histomorphometry Techniques" by Nicolette Jackson, Michel Assad, Derick Vollmer, James Stanley and Madeleine Chagnon. Today, we'll review pertinent insights into histology techniques used to obtain high quality histology slides for preclinical medical device pathology studies.