Content Library

StageBio pathologists were members of the STP SRPC Medical Device Implant Site Evaluation working group that published a recent Points to Consider article in Toxicologic Pathology

Complex biological responses are induced by implanted medical devices, and nonclinical studies are a common and often critical step for the safety assessment of these devices.

StageBio pathologists co-author article on the underestimated role ASN (autophagy of sensory neurons) plays in sensory ganglia

Many pathologists do not evaluate sensory ganglia in cynomolgus monkeys (Macaca fascicularis) during nonclinical toxicology investigations.

StageBio Pathologists Co-author Article Demonstrating Wound Dressings with High Evaporation Rates Improve Healing

Proper and effective wound care mandates the controlling of the homeostatic wound state.

StageBio pathologist co-authors review on contributing lifestyle factors of oral cancer

The National Toxicology Program (NTP) has conducted more than 500 short-term and 2-year toxicology and carcinogenicity studies in rodents: throughout the course of these studies, several chemicals tested contributed to the development of oral cancer.

The use of 3D-printed scaffolds to treat midfacial critical-sized bone defects

StageBio senior pathologist co-authors study on the use of 3D-printed bioactive scaffolds for restoring midfacial bone defects.

StageBio pathologists are members of the INHAND working group for CNS and PNS of the rat and mouse

IThe International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (INHAND) has published an article, “Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems: New and Revised INHAND Terms,” which can be accessed here. This article revises two existing terms and defines nine new terms for the rat and mouse central nervous system (CNS) and peripheral nervous system (PNS).

StageBio pathologist co-authors study on shape memory polymer foam-coated coils for the treatment of aneurysms

Healthcare providers often rely on embolic coils to isolate a patient’s aneurysm from artery blood flow and prevent rupturing. However, embolic coils are associated with complications such as recanalization, compacted coils (as a result of pulsing arterial flow), improper healing of an aneurysm, and others—all of which may result in the growth or rupturing of an aneurysm, as well as the creation of additional aneurysms.

3 Keys to Successful Pathology Endpoints in Inhalation Toxicology Studies

In a recent ACT 2021 Talking Tox webinar titled “Safety of E-Cigarette Products – A Toxicological Challenge,” I provided scientific guidance on pathology endpoints for inhalation studies. During my segment, I discussed the special planning necessary to optimize histopathology results when studying test articles dosed via the inhalation route (nose-only, head, or whole-body exposure).

Upcoming Events

ACVP Conference

Date: November 12-15, 2022
Location: Boston, MA
The 2022 American College of Veterinary Pathologists annual meeting in Boston, MA! We hope to see you there, stop by and see us at Booth #304! Contact us at info@stagebio.com for more information.

Learn more about StageBio’s COVID-19 response